The Reaction of Cinnoline 2-Oxides with Phenylmagnesium Bromide
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چکیده
منابع مشابه
determinant of the hankel matrix with binomial entries
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متن کاملOn the Synthesis and Reactivity of 4-(Oxiran-2-ylmethoxy)cinnoline: Targeting a Cinnoline Analogue of Propranolol
The title compound (2) was prepared by reaction of 4-chlorocinnoline with glycidol/sodium hydride in dry DMF, since treatment of cinnolin-4-ol with epichlorohydrin as well as oxidation of 4-allyloxycinnoline did not succeed. Reaction of 2 with primary and secondary amines leads to aminoalcohols characterized by a high tendency to rearrangement and/or elimination. The obtained products were subj...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 1970
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.18.1497